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The role of hepatic transferrin receptor 2 in the regulation of iron homeostasis in the body
Fine-tuning of body iron is required to prevent diseases such as iron-overload and anemia. The putative iron sensor, transferrin receptor 2 (TfR2), is expressed in the liver and mutations in this protein result in the iron-overload disease Type III hereditary hemochromatosis (HH). With the loss of f...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944196/ https://ncbi.nlm.nih.gov/pubmed/24639653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00034 |
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