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The role of hepatic transferrin receptor 2 in the regulation of iron homeostasis in the body

Fine-tuning of body iron is required to prevent diseases such as iron-overload and anemia. The putative iron sensor, transferrin receptor 2 (TfR2), is expressed in the liver and mutations in this protein result in the iron-overload disease Type III hereditary hemochromatosis (HH). With the loss of f...

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Hlavní autoři: Worthen, Christal A., Enns, Caroline A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944196/
https://ncbi.nlm.nih.gov/pubmed/24639653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00034
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