Nanog1 in NTERA-2 and Recombinant NanogP8 from Somatic Cancer Cells Adopt Multiple Protein Conformations and Migrate at Multiple M.W Species

Human Nanog1 is a 305-amino acid (aa) homeodomain-containing transcription factor critical for the pluripotency of embryonic stem (ES) and embryonal carcinoma (EC) cells. Somatic cancer cells predominantly express a retrogene homolog of Nanog1 called NanogP8, which is ∼99% similar to Nanog at the aa...

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Detalhes bibliográficos
Main Authors: Liu, Bigang, Badeaux, Mark D., Choy, Grace, Chandra, Dhyan, Shen, Irvin, Jeter, Collene R., Rycaj, Kiera, Lee, Chia-Fang, Person, Maria D., Liu, Can, Chen, Yueping, Shen, Jianjun, Jung, Sung Yun, Qin, Jun, Tang, Dean G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944193/
https://ncbi.nlm.nih.gov/pubmed/24598770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090615
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