Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model

This project was undertaken to address a critical cancer biology question: Is overexpression of the pluripotency molecule Nanog sufficient to initiate tumor development in a somatic tissue? Nanog1 is critical for the self-renewal and pluripotency of ES cells, and its retrotransposed homolog, NanogP8...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Bigang, Gong, Shuai, Li, Qiuhui, Chen, Xin, Moore, John, Suraneni, Mahipal V., Badeaux, Mark D., Jeter, Collene R., Shen, Jianjun, Mehmood, Rashid, Fan, Qingxia, Tang, Dean G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581066/
https://ncbi.nlm.nih.gov/pubmed/28881767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17186
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados