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Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells

The need for an intact immune system for cancer radiation therapy to be effective suggests that radiation not only acts directly on the tumor but also indirectly, through the activation of host immune components. Recent studies demonstrated that endogenous type I interferons (type I IFNs) play a rol...

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Autori principali: Lim, Joanne Y. H., Gerber, Scott A., Murphy, Shawn P., Lord, Edith M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944132/
https://ncbi.nlm.nih.gov/pubmed/24357146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1506-7
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