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Rho GEFs in endothelial junctions: Effector selectivity and signaling integration determine junctional response

Rho GTPases are cytoskeleton-regulating proteins that mediate the formation of intercellular junctions. Their localized activation by Rho GEFs (guanine-nucleotide exchange factors) and the selective activation of downstream effectors have emerged as areas of active research in the cell adhesion fiel...

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Autors principals: Ngok, Siu P, Anastasiadis, Panos Z
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943849/
https://ncbi.nlm.nih.gov/pubmed/24790803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/tisb.27132
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