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Mechanistic insights from functional characterization of an unnatural His37 mutant of the influenza A/M2 protein

The influenza A/M2 protein is a homotetrameric single-pass integral membrane protein encoded by the influenza A viral genome. Its transmembrane domain represents both a crucial drug target and a minimalistic model system for transmembrane proton transport and charge stabilization. Recent structural...

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Bibliografiske detaljer
Main Authors: Polishchuk, Alexei L., Cristian, Lidia, Pinto, Lawrence H., Lear, James D., DeGrado, William F.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943701/
https://ncbi.nlm.nih.gov/pubmed/24269540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2013.11.011
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