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Tropomyosin movement on F-actin during muscle activation explained by energy landscapes

Muscle contraction is regulated by tropomyosin movement across the thin filament surface, which exposes or blocks myosin-binding sites on actin. Recent atomic structures of F-actin-tropomyosin have yielded the positions of tropomyosin on myosin-free and myosin-decorated actin. Here, the repositionin...

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Bibliografische gegevens
Hoofdauteurs: Orzechowski, Marek, Moore, Jeffrey R., Fischer, Stefan, Lehman, William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943668/
https://ncbi.nlm.nih.gov/pubmed/24412204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.01.001
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