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The structural dynamics of α-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules

Coiled-coil tropomyosin, localized on actin filaments in virtually all eukaryotic cells, serves as a gatekeeper regulating access of the motor protein myosin and other actin-binding proteins onto the thin filament surface. Tropomyosin's modular pseudo-repeating pattern of approximately 39 amino...

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Detalhes bibliográficos
Main Authors: Lehman, William, Li, Xiaochuan (Edward), Orzechowski, Marek, Fischer, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962804/
https://ncbi.nlm.nih.gov/pubmed/24071513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2013.09.011
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