Hypomethylation signature of tumor-initiating cells predicts poor prognosis of ovarian cancer patients

DNA methylation contributes to tumor formation, development and metastasis. Epigenetic dysregulation of stem cells is thought to predispose to malignant development. The clinical significance of DNA methylation in ovarian tumor-initiating cells (OTICs) remains unexplored. We analyzed the methylomic...

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Main Authors: Liao, Yu-Ping, Chen, Lin-Yu, Huang, Rui-Lan, Su, Po-Hsuan, Chan, Michael W.Y., Chang, Cheng-Chang, Yu, Mu-Hsien, Wang, Peng-Hui, Yen, Ming-Shyen, Nephew, Kenneth P., Lai, Hung-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943526/
https://ncbi.nlm.nih.gov/pubmed/24256813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt583
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