Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancer

Pyruvate kinase M2 (PKM2) regulates glycolysis and oxidative phosphorylation; however, the role of PKM2 in ovarian cancer remains largely unknown. We investigated whether ovarian cancer metabolism could provide insight into the development of therapeutic strategies. We performed immunohistochemical...

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Vydáno v:PLoS One
Hlavní autoři: Chao, Tai-Kuang, Huang, Tien-Shuo, Liao, Yu-Ping, Huang, Rui-Lan, Su, Po-Hsuan, Shen, Hueng-Yuan, Lai, Hung-Cheng, Wang, Yu-Chi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533430/
https://ncbi.nlm.nih.gov/pubmed/28753677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182166
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