Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients

BACKGROUND: The dysregulation of transforming growth factor-β (TGF-β) signaling plays a crucial role in ovarian carcinogenesis and in maintaining cancer stem cell properties. Classified as a member of the ATP-binding cassette (ABC) family, ABCA1 was previously identified by methylated DNA immunoprec...

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Dades bibliogràfiques
Publicat a:Clin Epigenetics
Autors principals: Chou, Jian-Liang, Huang, Rui-Lan, Shay, Jacqueline, Chen, Lin-Yu, Lin, Sheng-Jie, Yan, Pearlly S, Chao, Wei-Ting, Lai, Yi-Hui, Lai, Yen-Ling, Chao, Tai-Kuang, Lee, Cheng-I, Tai, Chien-Kuo, Wu, Shu-Fen, Nephew, Kenneth P, Huang, Tim H-M, Lai, Hung-Cheng, Chan, Michael W Y
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307187/
https://ncbi.nlm.nih.gov/pubmed/25628764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-014-0036-2
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