Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array

BACKGROUND: The Illumina HumanMethylation450 BeadChip (HM450K) measures the DNA methylation of 485,512 CpGs in the human genome. The technology relies on hybridization of genomic fragments to probes on the chip. However, certain genomic factors may compromise the ability to measure methylation using...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Naeem, Haroon, Wong, Nicholas C, Chatterton, Zac, Hong, Matthew K H, Pedersen, John S, Corcoran, Niall M, Hovens, Christopher M, Macintyre, Geoff
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Methodology Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943510/
https://ncbi.nlm.nih.gov/pubmed/24447442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-51
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