Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy

Chronic myeloid leukemia and systemic mastocytosis are myeloid neoplasms sharing a number of pathogenetic and clinical features. In both conditions, an aberrantly activated oncoprotein with tyrosine kinase activity, namely BCR-ABL1 in chronic myeloid leukemia, and mutant KIT, mostly KIT D816V, in sy...

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Bibliografiska uppgifter
Huvudupphovsmän: Bibi, Siham, Arslanhan, Melis Dilara, Langenfeld, Florent, Jeanningros, Sylvie, Cerny-Reiterer, Sabine, Hadzijusufovic, Emir, Tchertanov, Luba, Moriggl, Richard, Valent, Peter, Arock, Michel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ferrata Storti Foundation 2014
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943304/
https://ncbi.nlm.nih.gov/pubmed/24598853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.098442
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