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Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
Hypoxia and free radicals, such as reactive oxygen and nitrogen species, can alter the function and/or activity of the transcription factor hypoxia-inducible factor 1 (HIF1). Interplay between free radicals, hypoxia and HIF1 activity is complex and can influence the earliest stages of tumour develop...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943205/ https://ncbi.nlm.nih.gov/pubmed/18500244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2397 |
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