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Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response

Hypoxia and free radicals, such as reactive oxygen and nitrogen species, can alter the function and/or activity of the transcription factor hypoxia-inducible factor 1 (HIF1). Interplay between free radicals, hypoxia and HIF1 activity is complex and can influence the earliest stages of tumour develop...

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Bibliografische gegevens
Hoofdauteurs: Dewhirst, Mark W., Cao, Yiting, Moeller, Benjamin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943205/
https://ncbi.nlm.nih.gov/pubmed/18500244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2397
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