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Facile synthesis of deuterated and [(14)C]labeled analogues of vanillin and curcumin for use as mechanistic and analytical tools

Curcumin is a dietary diphenol with antioxidant, antinflammatory and antitumor activity. We describe facile procedures for the synthesis of [(14)C(2)]curcumin (4 mCi/mmol), [d(6)]curcumin, [d(3)]curcumin, [(13)C(5)]curcumin, and [d(6)]bicyclopentadione, the major oxidative metabolite of curcumin. We...

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Main Authors: Gordon, Odaine N., Graham, Leigh A., Schneider, Claus
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943166/
https://ncbi.nlm.nih.gov/pubmed/24339007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3102
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