Cyclic Enkephalins with a Diversely Substituted Guanidine Bridge or a Thiourea Bridge: Synthesis, Biological and Structural Evaluations

[Image: see text] Two series of 22 and 15 atom cyclic enkephalins incorporating a diversely substituted guanidine bridge have been prepared to assess the potential effect of the bridge substitutions on their opioid activity profile. The most notable results were obtained with the shortest cyclic ana...

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Bibliografski detalji
Glavni autori: Touati-Jallabe, Youness, Bojnik, Engin, Legrand, Baptiste, Mauchauffée, Elodie, Chung, Nga N., Schiller, Peter W., Benyhe, Sandor, Averlant-Petit, Marie-Christine, Martinez, Jean, Hernandez, Jean-Franćois
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942877/
https://ncbi.nlm.nih.gov/pubmed/23822516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4008592
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