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Cyclic Enkephalins with a Diversely Substituted Guanidine Bridge or a Thiourea Bridge: Synthesis, Biological and Structural Evaluations

[Image: see text] Two series of 22 and 15 atom cyclic enkephalins incorporating a diversely substituted guanidine bridge have been prepared to assess the potential effect of the bridge substitutions on their opioid activity profile. The most notable results were obtained with the shortest cyclic ana...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Touati-Jallabe, Youness, Bojnik, Engin, Legrand, Baptiste, Mauchauffée, Elodie, Chung, Nga N., Schiller, Peter W., Benyhe, Sandor, Averlant-Petit, Marie-Christine, Martinez, Jean, Hernandez, Jean-Franćois
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942877/
https://ncbi.nlm.nih.gov/pubmed/23822516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4008592
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