Fus1/Tusc2 Is a Novel Regulator of Mitochondrial Calcium Handling, Ca(2+)-Coupled Mitochondrial Processes, and Ca(2+)-Dependent NFAT and NF-κB Pathways in CD4(+) T Cells

Aims: Fus1 has been established as mitochondrial tumor suppressor, immunomodulator, and antioxidant protein, but molecular mechanism of these activities remained to be identified. Based on putative calcium-binding and myristoyl-binding domains that we identified in Fus1, we explored our hypothesis t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Uzhachenko, Roman, Ivanov, Sergey V., Yarbrough, Wendell G., Shanker, Anil, Medzhitov, Ruslan, Ivanova, Alla V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2014
Pynciau:
Original Research Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942676/
https://ncbi.nlm.nih.gov/pubmed/24328503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5437
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg