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Fus1/Tusc2 Is a Novel Regulator of Mitochondrial Calcium Handling, Ca(2+)-Coupled Mitochondrial Processes, and Ca(2+)-Dependent NFAT and NF-κB Pathways in CD4(+) T Cells

Aims: Fus1 has been established as mitochondrial tumor suppressor, immunomodulator, and antioxidant protein, but molecular mechanism of these activities remained to be identified. Based on putative calcium-binding and myristoyl-binding domains that we identified in Fus1, we explored our hypothesis t...

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Detalhes bibliográficos
Main Authors: Uzhachenko, Roman, Ivanov, Sergey V., Yarbrough, Wendell G., Shanker, Anil, Medzhitov, Ruslan, Ivanova, Alla V.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942676/
https://ncbi.nlm.nih.gov/pubmed/24328503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5437
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