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Altered Endoribonuclease Activity of Apurinic/Apyrimidinic Endonuclease 1 Variants Identified in the Human Population

Apurinic/apyrimidinic endonuclease 1 (APE1) is the major mammalian enzyme in the DNA base excision repair pathway and cleaves the DNA phosphodiester backbone immediately 5′ to abasic sites. APE1 also has 3′-5′ DNA exonuclease and 3′ DNA phosphodiesterase activities, and regulates transcription facto...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kim, Wan Cheol, Ma, Conan, Li, Wai-Ming, Chohan, Manbir, Wilson III, David M., Lee, Chow H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942487/
https://ncbi.nlm.nih.gov/pubmed/24595156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090837
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