JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins

Targeted gene disruption studies have established that the c-Jun NH(2)-terminal kinase (JNK) is required for the stress-induced release of mitochondrial cytochrome c and apoptosis, and that the Bax subfamily of Bcl-2-related proteins is essential for JNK-dependent apoptosis. However, the mechanism b...

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Bibliografiset tiedot
Päätekijät: Tsuruta, Fuminori, Sunayama, Jun, Mori, Yasunori, Hattori, Seisuke, Shimizu, Shigeomi, Tsujimoto, Yoshihide, Yoshioka, Katsuji, Masuyama, Norihisa, Gotoh, Yukiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2004
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC394248/
https://ncbi.nlm.nih.gov/pubmed/15071501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600194
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