JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins
Targeted gene disruption studies have established that the c-Jun NH(2)-terminal kinase (JNK) is required for the stress-induced release of mitochondrial cytochrome c and apoptosis, and that the Bax subfamily of Bcl-2-related proteins is essential for JNK-dependent apoptosis. However, the mechanism b...
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| Udgivet i: | EMBO J |
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| Principais autores: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15071501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600194 |
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