Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

The eucaryotic translation initiation factor 4B (eIF4B) stimulates the helicase activity of the DEAD box protein eIF4A to unwind inhibitory secondary structure in the 5′ untranslated region of eucaryotic mRNAs. Here, using phosphopeptide mapping and a phosphospecific antiserum, we identify a serum-r...

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Publié dans:	EMBO J
Auteurs principaux:	Raught, Brian, Peiretti, Franck, Gingras, Anne-Claude, Livingstone, Mark, Shahbazian, David, Mayeur, Greg L, Polakiewicz, Roberto D, Sonenberg, Nahum, Hershey, John WB
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2004
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15071500/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600193
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