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Phosphorylation of Eukaryotic Translation Initiation Factor 4E Is Critical for Growth

Eukaryotic translation initiation factor 4E (eIF4E) binds to the cap structure at the 5′ end of mRNAs and is a critical target for the control of protein synthesis. eIF4E is phosphorylated in many systems in response to extracellular stimuli, but biochemical evidence to date has been equivocal as to...

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Autors principals: Lachance, Pascal E. D., Miron, Mathieu, Raught, Brian, Sonenberg, Nahum, Lasko, Paul
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC135594/
https://ncbi.nlm.nih.gov/pubmed/11865045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1656-1663.2002
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