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Phosphorylation of Eukaryotic Translation Initiation Factor 4E Is Critical for Growth

Eukaryotic translation initiation factor 4E (eIF4E) binds to the cap structure at the 5′ end of mRNAs and is a critical target for the control of protein synthesis. eIF4E is phosphorylated in many systems in response to extracellular stimuli, but biochemical evidence to date has been equivocal as to...

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Udgivet i:Mol Cell Biol
Principais autores: Lachance, Pascal E. D., Miron, Mathieu, Raught, Brian, Sonenberg, Nahum, Lasko, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135594/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11865045/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.6.1656-1663.2002
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