Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

The eucaryotic translation initiation factor 4B (eIF4B) stimulates the helicase activity of the DEAD box protein eIF4A to unwind inhibitory secondary structure in the 5′ untranslated region of eucaryotic mRNAs. Here, using phosphopeptide mapping and a phosphospecific antiserum, we identify a serum-r...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Raught, Brian, Peiretti, Franck, Gingras, Anne-Claude, Livingstone, Mark, Shahbazian, David, Mayeur, Greg L, Polakiewicz, Roberto D, Sonenberg, Nahum, Hershey, John WB
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2004
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15071500/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600193
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