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Mutant TDP-43 Deregulates AMPK Activation by PP2A in ALS Models
Bioenergetic abnormalities and metabolic dysfunction occur in amyotrophic lateral sclerosis (ALS) patients and genetic mouse models. However, whether metabolic dysfunction occurs early in ALS pathophysiology linked to different ALS genes remains unclear. Here, we investigated AMP-activated protein k...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3942426/ https://ncbi.nlm.nih.gov/pubmed/24595038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090449 |
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