In vitro Activation of heme oxygenase-2 by menadione and its analogs

BACKGROUND: Previously, we reported that menadione activated rat, native heme oxygenase-2 (HO-2) and human recombinant heme oxygenase-2 selectively; it did not activate spleen, microsomal heme oxygenase-1. The purpose of this study was to explore some structure–activity relationships of this activat...

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Detalhes bibliográficos
Main Authors: Vukomanovic, Dragic, Rahman, Mona N, Bilokin, Yaroslav, Golub, Andriy G, Brien, James F, Szarek, Walter A, Jia, Zongchao, Nakatsu, Kanji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942077/
https://ncbi.nlm.nih.gov/pubmed/24533775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-9912-4-4
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