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Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome

Epigenetic information is available from contemporary organisms, but is difficult to track back in evolutionary time. Here, we show that genome-wide epigenetic information can be gathered directly from next-generation sequence reads of DNA isolated from ancient remains. Using the genome sequence dat...

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Bibliografski detalji
Glavni autori: Pedersen, Jakob Skou, Valen, Eivind, Velazquez, Amhed M. Vargas, Parker, Brian J., Rasmussen, Morten, Lindgreen, Stinus, Lilje, Berit, Tobin, Desmond J., Kelly, Theresa K., Vang, Søren, Andersson, Robin, Jones, Peter A., Hoover, Cindi A., Tikhonov, Alexei, Prokhortchouk, Egor, Rubin, Edward M., Sandelin, Albin, Gilbert, M. Thomas P., Krogh, Anders, Willerslev, Eske, Orlando, Ludovic
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941110/
https://ncbi.nlm.nih.gov/pubmed/24299735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.163592.113
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