Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome

Epigenetic information is available from contemporary organisms, but is difficult to track back in evolutionary time. Here, we show that genome-wide epigenetic information can be gathered directly from next-generation sequence reads of DNA isolated from ancient remains. Using the genome sequence dat...

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Autors principals: Pedersen, Jakob Skou, Valen, Eivind, Velazquez, Amhed M. Vargas, Parker, Brian J., Rasmussen, Morten, Lindgreen, Stinus, Lilje, Berit, Tobin, Desmond J., Kelly, Theresa K., Vang, Søren, Andersson, Robin, Jones, Peter A., Hoover, Cindi A., Tikhonov, Alexei, Prokhortchouk, Egor, Rubin, Edward M., Sandelin, Albin, Gilbert, M. Thomas P., Krogh, Anders, Willerslev, Eske, Orlando, Ludovic
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941110/
https://ncbi.nlm.nih.gov/pubmed/24299735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.163592.113
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