Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome

Epigenetic information is available from contemporary organisms, but is difficult to track back in evolutionary time. Here, we show that genome-wide epigenetic information can be gathered directly from next-generation sequence reads of DNA isolated from ancient remains. Using the genome sequence dat...

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Detalhes bibliográficos
Main Authors: Pedersen, Jakob Skou, Valen, Eivind, Velazquez, Amhed M. Vargas, Parker, Brian J., Rasmussen, Morten, Lindgreen, Stinus, Lilje, Berit, Tobin, Desmond J., Kelly, Theresa K., Vang, Søren, Andersson, Robin, Jones, Peter A., Hoover, Cindi A., Tikhonov, Alexei, Prokhortchouk, Egor, Rubin, Edward M., Sandelin, Albin, Gilbert, M. Thomas P., Krogh, Anders, Willerslev, Eske, Orlando, Ludovic
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
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Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941110/
https://ncbi.nlm.nih.gov/pubmed/24299735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.163592.113
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