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Activation of DNA ligase by poly(ADP-ribose) in chromatin.

To elucidate the molecular mechanism by which poly(ADP-ribose) participates in DNA excision repair, we examined the effect of poly(ADP-ribose) on DNA ligase activity in DNA/histone and reconstituted chromatin systems. The ligase activity was markedly inhibited by histones; the inhibition varied depe...

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Autors principals: Ohashi, Y, Ueda, K, Kawaichi, M, Hayaishi, O
Format: Artigo
Idioma:Inglês
Publicat: 1983
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC394098/
https://ncbi.nlm.nih.gov/pubmed/6407017
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