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Activation of DNA ligase by poly(ADP-ribose) in chromatin.

To elucidate the molecular mechanism by which poly(ADP-ribose) participates in DNA excision repair, we examined the effect of poly(ADP-ribose) on DNA ligase activity in DNA/histone and reconstituted chromatin systems. The ligase activity was markedly inhibited by histones; the inhibition varied depe...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ohashi, Y, Ueda, K, Kawaichi, M, Hayaishi, O
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394098/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6407017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.12.3604
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