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Osteosarcoma Microenvironment: Whole-Slide Imaging and Optimized Antigen Detection Overcome Major Limitations in Immunohistochemical Quantification

BACKGROUND: In osteosarcoma survival rates could not be improved over the last 30 years. Novel biomarkers are warranted to allow risk stratification of patients for more individual treatment following initial diagnosis. Although previous studies of the tumor microenvironment have identified promisin...

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Detalhes bibliográficos
Main Authors: Kunz, Pierre, Fellenberg, Jörg, Moskovszky, Linda, Sápi, Zoltan, Krenacs, Tibor, Poeschl, Johannes, Lehner, Burkhard, Szendrõi, Miklos, Ewerbeck, Volker, Kinscherf, Ralf, Fritzsching, Benedikt
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940945/
https://ncbi.nlm.nih.gov/pubmed/24594971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090727
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