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Elevated ratio of MMP2/MMP9 activity is associated with poor response to chemotherapy in osteosarcoma

BACKGROUND: Matrix metalloproteinases (MMPs) are crucially involved in the regulation of multiple stages of cancer progression. Elevated MMP levels have been associated with the development of metastases and poor prognosis in several types of cancer. However, the role of MMPs in osteosarcoma and the...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Kunz, Pierre, Sähr, Heiner, Lehner, Burkhard, Fischer, Christian, Seebach, Elisabeth, Fellenberg, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793522/
https://ncbi.nlm.nih.gov/pubmed/26979530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2266-5
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