CD8(+)/FOXP3(+)-ratio in osteosarcoma microenvironment separates survivors from non-survivors: a multicenter validated retrospective study

Osteosarcoma is the most common primary bone tumor characterized by juvenile onset, tumor heterogeneity, and early pulmonary metastasis. Therapeutic improvement stagnates since more than two decades. Unlike major malignancies, biomarkers as prognostic factors at time of diagnosis are missing. Diseas...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Fritzsching, Benedikt, Fellenberg, Joerg, Moskovszky, Linda, Sápi, Zoltan, Krenacs, Tibor, Machado, Isidro, Poeschl, Johannes, Lehner, Burkhard, Szendrõi, Miklos, Bosch, Antonio Llombart, Bernd, Ludger, Csóka, Monika, Mechtersheimer, Gunhild, Ewerbeck, Volker, Kinscherf, Ralf, Kunz, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404826/
https://ncbi.nlm.nih.gov/pubmed/25949908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.990800
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