CD8(+)/FOXP3(+)-ratio in osteosarcoma microenvironment separates survivors from non-survivors: a multicenter validated retrospective study

Osteosarcoma is the most common primary bone tumor characterized by juvenile onset, tumor heterogeneity, and early pulmonary metastasis. Therapeutic improvement stagnates since more than two decades. Unlike major malignancies, biomarkers as prognostic factors at time of diagnosis are missing. Diseas...

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Vydáno v:Oncoimmunology
Hlavní autoři: Fritzsching, Benedikt, Fellenberg, Joerg, Moskovszky, Linda, Sápi, Zoltan, Krenacs, Tibor, Machado, Isidro, Poeschl, Johannes, Lehner, Burkhard, Szendrõi, Miklos, Bosch, Antonio Llombart, Bernd, Ludger, Csóka, Monika, Mechtersheimer, Gunhild, Ewerbeck, Volker, Kinscherf, Ralf, Kunz, Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404826/
https://ncbi.nlm.nih.gov/pubmed/25949908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.990800
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