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Identification of an Inhibitory Mechanism of Luteolin on Insulin-like Growth Factor-1 Ligand-receptor Interaction
Using single-molecule force measurement and single-molecule fluorescence imaging, we demonstrated that luteolin is able to perform an inhibitory effect on IGF-1 ligand-receptor binding, the initial step of IGF-1 signaling. Furthermore, this inhibition mechanism was also confirmed by flow cytometry a...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3940256/ https://ncbi.nlm.nih.gov/pubmed/23630137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300082 |
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