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Polycation-Functionalized Nanoporous Silicon Particles for Gene Silencing on Breast Cancer Cells

Nanoporous silicon particles (pSi), with a pore size in the range of 20~60 nm, were modified with polyethyleimine (PEI) to yield pSi-PEI particles, which were subsequently complexed with siRNA. Thus, pSi-PEI/siRNA particles were fabricated, with the PEI/siRNA nanocomplexes mainly anchored inside the...

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Detalhes bibliográficos
Main Authors: Zhang, Mingzhen, Xu, Rong, Xia, Xiaojun, Yang, Yong, Gu, Jianhua, Qin, Guoting, Liu, Xuewu, Ferrari, Mauro, Shen, Haifa
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842233/
https://ncbi.nlm.nih.gov/pubmed/24103653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.09.033
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