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Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors

SRC is a tyrosine kinase that plays a role in oncogenic, invasive and bone-metastatic processes. It has therefore been prioritized as a candidate therapeutic target in patients with solid tumors. Several SRC inhibitors are now in development, of which dasatinib has been most explored. Preclinical st...

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Sonraí Bibleagrafaíochta
Main Authors: Araujo, John, Logothetis, Christopher
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940067/
https://ncbi.nlm.nih.gov/pubmed/20226597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2010.02.015
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