Inhibitors of TonB Function Identified by a High-Throughput Screen for Inhibitors of Iron Acquisition in Uropathogenic Escherichia coli CFT073

The urinary tract is one of the most common sites of infection in humans, and uropathogenic Escherichia coli (UPEC) is the main causative agent of urinary tract infections. Bacteria colonizing the urinary tract face extremely low iron availability. To counteract this, UPEC expresses a wide variety o...

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Bibliographic Details
Main Authors: Yep, Alejandra, McQuade, Thomas, Kirchhoff, Paul, Larsen, Martha, Mobley, Harry L. T.
Format: Artigo
Language:Inglês
Published: American Society of Microbiology 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940036/
https://ncbi.nlm.nih.gov/pubmed/24570372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01089-13
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