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Structural insights into the effects of 2′-5′ linkages on the RNA duplex
The mixture of 2′-5′ and 3′-5′ linkages generated during the nonenzymatic replication of RNA has long been regarded as a central problem for the origin of the RNA world. However, we recently observed that both a ribozyme and an RNA aptamer retain considerable functionality in the presence of prebiot...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939906/ https://ncbi.nlm.nih.gov/pubmed/24516151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317799111 |
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