EZH2 expands breast stem cells through activation of NOTCH1 signaling

Breast cancer is the second-leading cause of cancer-related deaths in women, but the details of how it begins remain elusive. Increasing evidence supports the association of aggressive triple-negative (TN) breast cancer with heightened expression of the Polycomb group protein Enhancer of Zeste Homol...

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Autors principals: Gonzalez, Maria E., Moore, Heather M., Li, Xin, Toy, Kathy A., Huang, Wei, Sabel, Michael S., Kidwell, Kelley M., Kleer, Celina G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939892/
https://ncbi.nlm.nih.gov/pubmed/24516139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308953111
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