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Minor class splicing shapes the zebrafish transcriptome during development

Minor class or U12-type splicing is a highly conserved process required to remove a minute fraction of introns from human pre-mRNAs. Defects in this splicing pathway have recently been linked to human disease, including a severe developmental disorder encompassing brain and skeletal abnormalities kn...

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Main Authors: Markmiller, Sebastian, Cloonan, Nicole, Lardelli, Rea M., Doggett, Karen, Keightley, Maria-Cristina, Boglev, Yeliz, Trotter, Andrew J., Ng, Annie Y., Wilkins, Simon J., Verkade, Heather, Ober, Elke A., Field, Holly A., Grimmond, Sean M., Lieschke, Graham J., Stainier, Didier Y. R., Heath, Joan K.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939875/
https://ncbi.nlm.nih.gov/pubmed/24516132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305536111
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