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The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model

Understanding liver development should lead to greater insights into liver diseases and improve therapeutic strategies. In a forward genetic screen for genes regulating liver development in zebrafish, we identified a mutant – oliver – that exhibits liver-specific defects. In oliver mutants, the live...

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Detalhes bibliográficos
Main Authors: Curado, Silvia, Ober, Elke A., Walsh, Susan, Cortes-Hernandez, Paulina, Verkade, Heather, Koehler, Carla M., Stainier, Didier Y. R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898538/
https://ncbi.nlm.nih.gov/pubmed/20483998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.004390
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