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tomm22 Knockdown-Mediated Hepatocyte Damages Elicit Both the Formation of Hybrid Hepatocytes and Biliary Conversion to Hepatocytes in Zebrafish Larvae

The liver has a highly regenerative capacity. In the normal liver, hepatocytes proliferate to restore lost liver mass. However, when hepatocyte proliferation is impaired, biliary epithelial cells (BECs) activate and contribute to hepatocytes. We previously reported in zebrafish that upon severe hepa...

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Bibliographic Details
Published in:Gene Expr
Main Authors: Wu, Jianchen, Choi, Tae-Young, Shin, Donghun
Format: Artigo
Language:Inglês
Published: Cognizant Communication Corporation 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542045/
https://ncbi.nlm.nih.gov/pubmed/28251883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221617X695195
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