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Paired toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12

Minimal requirements for generating effective immunity include the delivery of antigenic (signal 1) and costimulatory (signal 2) signals to T lymphocytes. Recently, a class of 3(rd) signals, often delivered by antigen-presenting dendritic cells, has been shown greatly to enhance immune responses, es...

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Autors principals: Zheng, Rongxiu, Cohen, Peter A., Paustian, Christopher A., Johnson, Terrence D., Lee, Walter T., Shu, Suyu, Koski, Gary K.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939830/
https://ncbi.nlm.nih.gov/pubmed/18519662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6669
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