Extracellular ATP and Toll-Like Receptor 2 Agonists Trigger in Human Monocytes an Activation Program That Favors T Helper 17

Strategically-paired Toll-like receptor (TLR) ligands induce a unique dendritic cell (DC) phenotype that polarizes Th1 responses. We therefore investigated pairing single TLR ligands with a non TLR-mediated danger signal to cooperatively induce distinct DC properties from cultured human monocytes. A...

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Detalhes bibliográficos
Main Authors: Paustian, Christopher, Taylor, Patricia, Johnson, Terrence, Xu, Min, Ramirez, Nancy, Rosenthal, Kenneth S., Shu, Suyu, Cohen, Peter A., Czerniecki, Brian J., Koski, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561418/
https://ncbi.nlm.nih.gov/pubmed/23382974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054804
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