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Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes

Recently, a new lineage of CD4(+) T cells has been described in the mouse that specifically secretes IL-17 [T helper (Th) 17]. This discovery has led to a revision of the hypothesis that many autoimmune diseases are predominantly a Th1 phenomenon and may instead be critically dependent on the presen...

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Detalhes bibliográficos
Main Authors: Evans, Hayley G., Suddason, Tesha, Jackson, Ian, Taams, Leonie S., Lord, Graham M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040448/
https://ncbi.nlm.nih.gov/pubmed/17942669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708426104
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