CD4(+)CD73(+) T cells are associated with lower T-cell activation and C reactive protein levels and are depleted in HIV-1 infection regardless of viral suppression

BACKGROUND: The role of the adenosine (ADO) suppression pathway, specifically CD39-expressing and CD73-expressing CD4(+) T cells in HIV-1 infection is unclear. METHODS: We evaluated the frequency and numbers of CD4(+)CD39(+) and CD4(+)CD73(+) T cells, activated T cells, and plasma C reactive protein...

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Main Authors: Schuler, Patrick J., Macatangay, Bernard J.C., Saze, Zenichiro, Jackson, Edwin K., Riddler, Sharon A., Buchanan, William G., Hilldorfer, Benedict B., Mellors, John W., Whiteside, Theresa L., Rinaldo, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939796/
https://ncbi.nlm.nih.gov/pubmed/24005375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328360c7f3
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