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Adenosine production by human B cells and B cell–mediated suppression of activated T cells

Antibody-independent role of B cells in modulating T-cell responses is incompletely understood. Freshly isolated or cultured B cells isolated from the peripheral blood of 30 normal donors were evaluated for CD39 and CD73 coexpression, the ability to produce adenosine 5′-monophosphate (AMP) and adeno...

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Detalhes bibliográficos
Main Authors: Saze, Zenichiro, Schuler, Patrick J., Hong, Chang-Sook, Cheng, Dongmei, Jackson, Edwin K., Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701906/
https://ncbi.nlm.nih.gov/pubmed/23678003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-482406
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